The heroic Italian, who in 2001 lost both legs in a Champ Car shunt, may again drive one of Sir Frank's cars.
Zanardi, who raced for the team in 1999 before returning to America, sat in the cockpit in the Imola garage to see if he could safely fit.
"I'm not afraid nor will I get emotional," the 38-year-old told an Italian newspaper.
"I fit almost perfectly. It will be real fun."